Polycomb Regulatory targets
Integrated from Multi-source Evidence
Human
Mouse

Introduction to PRIME

PRIME is an integrative resource for Polycomb regulatory complex targets across two species and 65 tissue types. It compiles and harmonizes Polycomb target gene data from 6,323 high-quality datasets, including ChIP-seq, RNA-seq, and 5,381 literature-mined records from 2,565 publications. PRIME features interactive visualization tools and an intuitive web interface, enabling efficient data exploration and hypothesis generation. This platform provides a valuable foundation for research on Polycomb-mediated gene regulation, development, and disease.

Database Statistics

Target Confidence
Bar Chart
Tissue Distribution
Bubble Chart

Key Features

Flexible Search

Multi-modal search capabilities including category, gene-based, and logic searches with tissue filtering.

Interactive Analysis

Comprehensive analysis tools for comparative studies, network analysis, disease associations, sequence motif analysis, and expression exploration.

Genome Browser

Interactive genomic visualization with ChIP-seq tracks and regulatory element annotations.

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